Bulk chromatin profiling

CUT&Tag

Profile selected histone marks across a bulk sample. We work with you on the target, controls, sample preparation, sequencing, and interpretation.

Service workflow diagram
A clearer view of your biology

The questions
you can explore.

This service is currently offered as bulk CUT&Tag. Results describe the sampled population rather than individual cells or nuclei.

  1. 01Where is a selected histone modification enriched?
  2. 02How do chromatin profiles differ between samples or conditions?
  3. 03Which regions can be connected with expression changes or candidate regulatory elements?
Your project outputs

Define what you need
for your next step.

Agreed project scope can include the following. Deliverables and analysis depth are specified during project design.

01

Targeted libraries

CUT&Tag libraries generated for the agreed antibody target and control design.

02

Sequencing & QC

Sequencing and sample-level quality summaries for the agreed project scope.

03

Enrichment profiles

Genome-wide enrichment tracks and peak calls when appropriate for the target.

04

Comparative analysis

Sample- or condition-level comparisons and integration with gene-expression or annotation information.

Bring us your sample and question.

We’ll help define the appropriate assay, controls, sequencing, and analysis scope.

Discuss this service